[1]王水,刘晓安,赵佳.联合法观察前哨淋巴通道的临床研究[J].中华乳腺病杂志(电子版),2007,1(1):55.
　WANG Shui,LIU Xiao-an,ZHAO Jia.The study on sentinel lymphatic channels by using methylene blue and technetium 99m sulfur colloid in breast cancer patients[J].Chinese Journal of Breast Disease (Electronic Version),2007,1(1):55.
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联合法观察前哨淋巴通道的临床研究()

中华乳腺病杂志（电子版）[ISSN:1674-0807/CN:11-9146/R]

卷:
第1卷
期数:
2007年1期
页码:
55
栏目:
临床研究
出版日期:
2007-02-01

文章信息/Info

Title:
The study on sentinel lymphatic channels by using methylene blue and technetium 99m sulfur colloid in breast cancer patients
作者:
王水;刘晓安;赵佳
南京医科大学第一附属医院普外科乳腺内分泌病区
Author(s):
WANG Shui;LIU Xiao-an;ZHAO Jia
关键词:
乳腺癌; 前哨淋巴结活检; 前哨淋巴通道; 99Tcm SC; 美蓝
摘要:
目的　探讨前哨淋巴通道（ＳＬＣ）的行走方向、途径、数量及其与前哨淋巴结（ＳＬＮ）之间的关系，以寻找乳腺癌ＳＬＮＢ出现假阴性的原因，并提出提高其检出率、减少假阴性的方法。方法　９３例Ⅰ ～Ⅱ期乳腺癌患者行术前核素法ＳＬＣ显像和术中染料法ＳＬＣ显像，并据ＳＬＣ行前哨淋巴结活检（ＳＬＮＢ）。结果　９３例中核素法和染料法同时成功显示ＳＬＣ和ＳＬＮ者８１例。大多数患者只有一条位于乳腺外上象限的ＳＬＣ，且主要集中在θｅ角为３１°～９０°的范围内，均终止于腋窝ＳＬＮ。沿ＳＬＣｓ解剖出的ＳＬＮ，病理结果未发现有假阴性和假阳性。结论　尚未发现乳腺癌腋窝“跳跃式”淋巴转移模式，推测ＳＬＮＢ假阴性的产生是技术问题，可能与手术者对ＳＬＣｓ和ＳＬＮ行走路线和数量的复杂性认识不足有直接关系。核素法与染料法各有优劣，两者联合，优势互补，通过术前核素显像对ＳＬＣ和ＳＬＮ的分布获得大致了解后，在术中仔细解剖沿蓝染ＳＬＣ寻找ＳＬＮ，可以有效的检出ＳＬＣ，并减少ＳＬＮＢ的假阴性率。

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更新日期/Last Update: 2007-01-20