[1]Chong,Le,等.Is it necessary to do axillary dissection in old women with breast cancer? A meta-analysis of randomized clinical trials[J].中华乳腺病杂志(电子版),2012,6(6):622-630.
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Is it necessary to do axillary dissection in old women with breast cancer? A meta-analysis of randomized clinical trials()

中华乳腺病杂志（电子版）[ISSN:1674-0807/CN:11-9146/R]

卷:
第6卷
期数:
2012年6期
页码:
622-630
栏目:
论著
出版日期:
2012-12-01

文章信息/Info

作者:
Chong;Le; ;Tian;Jin-hui; ;Gu;Jing; ;Yang;Ke-hu
Evidence-Based Medical Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, Gansu Province, China
关键词:
breast neoplasms;  axillary dissection;  meta-analysis;  randomized controlled trials
摘要:
Objective　To assess the effectiveness and safety of axillary dissection in old women with breast cancer. Methods　All randomized controlled trials on axillary dissection in old woman were retrieved in the Cochrane Library, PubMed, EMBASE and Chinese Biomedical Literature Database. Meta-analyses were completed using RevMan 5.1. Results　Three eligible randomized controlled trials (RCTs) including 5337 patients were involved. There were weak evidences in favor of axillary dissection in old woman. The meta-analysis showed that the overall survival (OS) in 1, 3, 5 and 7 years and the disease-free survival (DFS) in 1, 3 and 5 years were not statistically different between axillary dissection patients and non-axillary dissection patients. However there was a statistical difference in 7-year DFS. Conclusions　Axillary dissection does not show a survival benefit in the old women with breast cancer. Therefore it is not well-founded to do axillary dissection in old women with breast cancer.

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更新日期/Last Update: 2012-01-20