[1]William Wai Nam Tsang,Wings Tjing Yung Loo,Louis Wing Cheong Chow,等.Effect of Tai Chi Chuan on serotonin and cortisol for monitoring stress and quality of life in post-treatment breast cancer patients[J].中华乳腺病杂志(电子版),2014,8(4):266-272.
　[J].Chinese Journal of Breast Disease (Electronic Version),2014,8(4):266-272.
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Effect of Tai Chi Chuan on serotonin and cortisol for monitoring stress and quality of life in post-treatment breast cancer patients
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中华乳腺病杂志（电子版）[ISSN:1674-0807/CN:11-9146/R]

卷:
第8卷
期数:
2014年4期
页码:
266-272
栏目:
论著
出版日期:
2014-08-01

文章信息/Info

作者:
William Wai Nam Tsang;  Wings Tjing Yung Loo;  Louis Wing Cheong Chow; Elizabeth Lam Yan Ng;  Adrian Yun San Yip;  Jianping Chen
Hong Kong Polytechnic University(William Wai Nam Tsang,Wings Tjing Yung Loo);UNIMED Medical Institute and Organisation for Oncology and Translational Research (Wings Tjing Yung Loo, Louis Wing Cheong Chow, Elizabeth Lam Yan Ng, Adrian Yun San Yip);University of Hong Kong (Jianping Chen)
关键词:
Tai Ji; Breast neoplasms; Quality of life; Serotonin
文献标志码:
A
摘要:
ObjectiveImmediate physical exercise has been recommended for patients in the recovery phase to improve survival and quality of life ( QOL) and reduce recurrence of disease. The new NCCN Guidelines for Survivorship also highlighted the role of exercise in post-cancer health, encouraging patients to perform light physical activity following treatment. The aim of our study is to effect of Tai Chi Chuan (TCC) on serotonin and cortisol for monitoring stress and QOL in post-treatment breast cancer patients. MethodsTotally 85 post-treatment breast cancer patients were enrolled in this study to observe the effects of practicing TCC on recovery, as well as stress and happiness which are indicators of QOL of in patients. Peripheral blood was drawn from study subjects to analyze the levels of serotonin, cortisol and high sensitive C-reactive protein(HS-CRP) at baseline, and at 3, 6 and 12 months of TCC practice. Blood was drawn from healthy subjects only at baseline. A QOL questionnaire was administered to study subjects at three time points throughout the study, and once for healthy controls. The data were processed by analysis of variance of repeated measurement. ResultsAt 3, 6and 12 months time points following regular TCC exercise, WBC, RBC, hemoglobin in blood samples showed a statistically significant difference (F = 161.55, 172.14, 289.73; all P = 0.00) ; the level of serotonin (biomarker for well-being), cortisol (indicator of stress) and HS-CRP (biomarker for inflammation) showed a statistical improvement (F = 307.46, 182.85, 102.23; all P = 0.00). After 3, 6 and 12 months of regular TCC exercise, according to the results of QOL questionnaire, the indicators including quality of sleep, perceived hunger, fatigue, contentment, stress and social interaction presented a significant difference (F =312.98, 222.64, 543.90,46.05,28.10,78.92, all P<0.05), while there was no statistical difference in life dissatisfaction (F = 56.61, P = 0. 166) ConclusionsTCC physical activity for post-treatment breast cancer patients improved QOL and overall well-being, leading to improved mental, physical and psychological functioning. Regulated levels of serotonin and cortisol mediated by TCC exercises are proved to be vital for continued good health.

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更新日期/Last Update: 2018-08-07