[1]梁全琨,张永松,钟玲,等.新辅助化疗对腔镜乳腺癌改良根治术后并发症 及疗效的影响[J].中华乳腺病杂志：电子版,2015,9(1):18-22.
　Impact of neoadjuvant chemotherapy on postoperative complications and effectiveness after endoscopic mastectomy for breast cancer[J].Chinese Journal of Breast Disease (Electronic Version),2015,9(1):18-22.
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新辅助化疗对腔镜乳腺癌改良根治术后并发症 及疗效的影响()

中华乳腺病杂志：电子版[ISSN:1674-0807/CN:11-9146/R]

卷:
第9卷
期数:
2015年1期
页码:
18-22
栏目:
论著
出版日期:
2015-02-01

文章信息/Info

Title:
Impact of neoadjuvant chemotherapy on postoperative complications and effectiveness after endoscopic mastectomy for breast cancer
作者:
梁全琨; 张永松; 钟玲; 范林军
 第三军医大学西南医院乳腺外科
关键词:
 ; 化学疗法; 辅助; 内窥镜; 乳腺肿瘤; 手术后并发症; 治疗结果
文献标志码:
A
摘要:
目的 评估新辅助化疗对腔镜乳腺癌改良根治术后并发症及疗效的影响。方法 共纳入接受腔镜手术的乳腺癌患者183例，其中98例首先给予新辅助化疗（新辅助化疗组），85例直接行腔镜改良根治术（对照组）。结果 两组手术时间、出血量、引流量无显著差异（p>0.05），新辅助化疗组术后感染发生率、上肢水肿发生率均低于对照组（3.1%vs5.9%和8.2%vs12.9%），但两组差异无统计学意义（p>0.05），两组在乳头或皮瓣坏死、局部复发、远处转移及总生存率方面也无显著差异（p>0.05）。结论 新辅助化疗不增加腔镜乳腺癌改良根治术后并发症的发生率，不做新辅助化疗也不影响腔镜乳腺癌改良根治术后的远期疗效。
Abstract:
Objective To evaluate the impact of neoadjuvant chemotherapy (NCT) on postoperative complications and effectiveness after endoscopic mastectomy for breast cancer. Methods We retrospectively reviewed 183 patients with advanced breast cancers who underwent endoscopic mastectomy,98 of them receive neoad- juvant chemotherapy before surgeries(the NCT group),and 85 of them receive endo- scopic mastectomy directely(the control group).Results There were no statistic difference between two groups in terms of operation times, amount of bleeding and drainage (p>0.05). Rates of infection and edema of the upper extremity in NCT group were lower than which in the control group(3. 1%vs5.9% and 8.2%vs12. 9%),but there showed no statistic difference(p>0.05). No statistic difference was observed between two groups in terms of necrosis of nipple or skin flap, local recurrence, distant metastasis and overall survival rate as well(p>0.05). Conclusion Neo- adjuvant chemotherapy did not increase postoperative complications after endoscopic mastectomy for breast cancer and the effect didn’t influenced by NCT.

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更新日期/Last Update: 2015-08-18